منابع مشابه
Intrathecal and epidural narcotics.
This paper presents an overall review of epidural and intrathecal narcotics. The early laboratory studies and initial clinical applications are presented. This is followed by a description of the mechanism of action of narcotics acting both intrathecally and epidurally, and some of the similarities and differences between narcotics and local anesthetic drugs. Technique, dosages, indications, an...
متن کاملEpidural, intrathecal pharmacokinetics, and intrathecal bioavailability of ropivacaine.
BACKGROUND Ropivacaine is used by the epidural route for postoperative pain management with various neuraxial techniques. Given the widespread use of these techniques and the relative paucity of data on spinal disposition of local anesthetics, we evaluated through an experimental animal model, the spinal disposition of ropivacaine, allowing further studies of factors influencing their intrathec...
متن کاملIntrathecal opioids and lower urinary tract function: a urodynamic evaluation.
BACKGROUND Intrathecal administration of opioids may cause lower urinary tract dysfunction. In this study, the authors compared the effects of morphine and sufentanil administered intrathecally in a randomized double-blind fashion (two doses each) on lower urinary tract function in healthy male volunteers. METHODS Urodynamic evaluation was performed before and every hour after drug administra...
متن کاملIntrathecal opioids plus bupivacaine: an option to prolong analgesic efficacy when using the combined spinal-epidural technique--a case report.
Providing analgesia in the latent phase of labor can be challenging. Many obstetricians and nurse midwives believe that epidural analgesia initiated too early in the course of labor can prolong labor and result in fetal malpresentation, thus increasing the need for instrumentation. Many practitioners therefore use the combined spinal-epidural technique with intrathecal opioids during the early ...
متن کاملEndocrine consequences of long-term intrathecal administration of opioids.
Intrathecal administration of opioids is a very efficient tool in the long-term control of intractable nonmalignant pain. However, despite the well known role of opioids in endocrine regulation, few data are available about possible effects on hypothalamic-pituitary function during this treatment. Seventy-three patients (29 men and 44 women; mean age, 49.2 +/- 11.7 yr) receiving opioids intrath...
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ژورنال
عنوان ژورنال: Anaesthesia and Intensive Care
سال: 1987
ISSN: 0310-057X,1448-0271
DOI: 10.1177/0310057x8701500108